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Synthesis of 14C-labelled bis-azo biphenyl dyes

✍ Scribed by D. Franklin Milam; Robert K. Lynn

Publisher: John Wiley and Sons
Year: 1983
Tongue: French
Weight: 199 KB
Volume: 20
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580200112

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✦ Synopsis

Two 14C-label l e d bis-azo biphenyl dyes have been prepared from u n i f o r m l y r i n g -l a b e l l e d 14C-benzidine and 14C-3,3'dimethylbenzidine. The amines were t e t r a -a z o t i z e d w i t h sodium n i t r i t e and HCL. D i r e c t Blue 6 was then prepared from t e t r a -a z o benzidine by a l l o w i n g i t t o r e a c t w i t h two equival e n t s of H a c i d (8-amino-l-naphthol-3,6-disulfonic a c i d mono sodium s a l t ) under basic conditions. Acid Red 114 was prepared from t e t r a -a z o 3,3'-dirnethylbenzidine by sequential r e a c t i o n w i t h one e q u i v a l e n t o f G a c i d (2-naphthol-6,8-disulfonic a c i d dipotassium s a l t ) f o l l o w e d by one equivalent o f phenol. This product was then e s t e r i f i e d w i t h p-toluenesulfonyl c h l o r i d e t o g i v e a c i d Red 114.

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