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Synthesis of a 13C,15N labeled imidazole and characterization of the 2,5-endoperoxide and its decomposition

✍ Scribed by Ping Kang; Christopher S Foote

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
55 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

A synthesis of 13 C, 15 N labeled imidazoles was developed which allows the direct detection of a transient 2,5-endoperoxide at -100°C. The endoperoxide was thoroughly characterized by 1 H, 13 C, and 15 N NMR. Upon warming, the endoperoxide decomposes via a series of transient intermediates to 13 CO 2 and 1,2-diphenyl-ethanediimine.

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