A synthesis of dl-9(O)-methano-A 6(9a)\_pGI 1 (1\_), a more potent prostacyclin analog than carbacyclin, has been accomplished utilizing regiocontrolled transformation of the enone to the olefin via the allylsilane as a key step.
Synthesis of 9(0)-Methano-Δ6(9α)-PGI1: The highly potent carbon analog of prostacyclin
✍ Scribed by Masakatsu Shibasaki; Yasuhiro Torisawa; Shiro Ikegami
- Book ID
- 104219992
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 227 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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