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Synthesis of 9-amino-, 9-aminomethyl-1,2,3,4-tetrahydro- and 1,2,3,4,5,6,7,8-octahydroacridine derivatives

✍ Scribed by Maria Rosaria Del Giudice; Anna Borioni; Carlo Mustazza; Franco Gatta

Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
613 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis

This paper describes the synthesis of 9-amino-2- and 4-hydroxy- and 2,4-dihydroxy-1,2,3,4-tetrahydroacridines 2 and of 9 -aminomethyl-1,2,3,4-tetrahydro- and 1,2,3,4,5,6,7,8-octahydroacridines 3 starting from the corresponding 9-carboxamido derivatives. A new synthetical pathway to 9-amino-2-hydroxyacridine 9 is also reported.

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