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SYNTHESIS OF [8-α-HYDROXYISOCAPROIC ACID] OXYTOCIN

✍ Scribed by ROY, J. ;GAZIS, D. ;SCHWARTZ, I.L.

Book ID
115097651
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
359 KB
Volume
16
Category
Article
ISSN
0367-8377

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## Abstract Starting from a selectively protected derivative of α,α′‐diaminosuberic acid (**3**) the linear protected peptide **11** has been obtained. Cyclisation to **12** followed by removal of the protecting groups by hydrogenolysis afforded the ‘dicarba’ analogue of oxytocin, **1 c**, which sh