๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of 8-aryltetrahydroisoquinolines as dopamine antagonists and evaluation for potential neuroleptic activity

โœ Scribed by Ellefson, Charles R.; Prodan, Kathleen A.; Brougham, Linda R.; Miller, Arni

Book ID
117988399
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
560 KB
Volume
23
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Synthesis and biological evaluation of p
Synthesis and biological evaluation of p-bromospiperone as potential neuroleptic drug
โœ C. C. Huang; A. M. Friedman; R. So; M. Simonovic; H. Y. Meltzer ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 369 KB

p-Bromospiperone was prepared from the reaction of spiperone with bromine. It was tested for dopamine receptor binding affinity in vitro and its ability to stimulate prolactin secretion in vivo. The results indicate no significant change of biological activities due to the bromination of spiperone.