Synthesis of 7-substituted-5-androstene derivatives promoted by SmI2
β Scribed by Qin Gu; Yun-Hong Zheng; Yuan-Chao Li
- Book ID
- 116891871
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 179 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0039-128X
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Substituted pyrrole derivatives are prepared by treatment of 2,3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the b-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tertbutyloxycarbonyl)-dehydroalanine methyl ester.