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Synthesis of 2,3,5-substituted pyrrole derivatives

✍ Scribed by Paula M.T. Ferreira; Hernâni L.S. Maia; Luı́s S. Monteiro

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
147 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

Substituted pyrrole derivatives are prepared by treatment of 2,3-dihydrofuran derivatives with trifluoroacetic acid. These in turn are obtained by Michael addition of carbon nucleophiles of the b-dicarbonyl type to N-(4-toluenesulfonyl)-N-(tertbutyloxycarbonyl)-dehydroalanine methyl ester.

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