𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 6β-Halogenodeoxyneopine from Neopine

✍ Scribed by Maat, L.; De Groot, J. A.; Beyerman, H. C.

Book ID
126307204
Publisher
Taylor and Francis Group
Year
1979
Tongue
English
Weight
206 KB
Volume
9
Category
Article
ISSN
0039-7911

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of neopine and its 5β- and 7-s
Synthesis of neopine and its 5β- and 7-substituted derivatives (chemistry of opium alkaloids, part XL≠)
✍ G. J. Meuzelaar; R. H. Woudenberg; A. Sinnema; L. Maat 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 649 KB

## Abstract Heating 14β‐bromocodeine (3) with methanol and triethylamine yielded 6α, 7α‐epoxy‐6‐deoxyneopine (5). The epoxide 5 was reduced to neopine (7) with lithium aluminium hydride, whereas reaction of 5 with sodium methoxide gave 7β‐methoxyneopine (9). Similar reactions were performed with 14

Partial synthesis of 6β-sesquiterpenolid
Partial synthesis of 6β-sesquiterpenolides from 6α-sesquiterpenolides
✍ José L. Bretón; Juan J. Cejudo; Andrés García-Granados; Andrés Parra; Francisco 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 206 KB

## AlSSTRAm Chemikai means were used to achieve the epimetimtion at C-4 of bu-eudesmanolides, with several ji4n&na&zations, to @udesmanolides. ## The process consists of the L.iAlH4 reduction of a 6a-iactone, selective acetyW of the hydmxymethyiene group at C-12 midclton and rerluction at C-4 to

Partial synthesis of 6β-eudesmanolides a
Partial synthesis of 6β-eudesmanolides and 6β-guaianolides from 6α-eudesmanolides: Synthesis of analogues of artepaulin, colartin and tannunolide D
✍ José L. Bretón; Juan J. Cejudo; Andrés García-Granados; Andrés Parra; Francisco 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 803 KB

Epimerization at C-6 of polyfimctionalized 6a-eudesmanolides was achieved by chemical means, to obtain 6ikwdesmanolides and, after rearrangement, 6p-guaianolides. The epimerization process consists of the LiAU$ reduction of a 6a-lactone, selective pmtection of the hydroxymethylene group at C-12, oxi

Synthesis of (β-methyl3H-6β-iodopenicill
Synthesis of (β-methyl3H-6β-iodopenicillanic acid
✍ Fabien De Meester; Jean-Marie Frère; Jean-Louis Piette; Hubert Vanderhaeghe 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 428 KB

A rapid and easy synthesis of tritium-labelled 8-iodopenicillanate, an efficient inactivator of serine B-lactamase, is described. This method involves only three reaction steps after the introduction of the label in the molecule with an overall yield of 16 % .