AbstractÐThe synthesis of a series of dierently substituted 8-chloro-benzo[c]quinolizin-3-ones, as potent and selective human steroid 5a-reductase type 1 inhibitors, has been accomplished by a four-step procedure based on the TiCl 4 -promoted tandem Mannich±Michael cyclization of 2-silyloxy-1,3-buta
✦ LIBER ✦
Synthesis of 6-azacholesten-3-ones: Potent inhibitors of 5α-reductase
✍ Scribed by Curt Haffner
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 178 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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