𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 6-azacholesten-3-ones: Potent inhibitors of 5α-reductase

✍ Scribed by Curt Haffner


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
178 KB
Volume
36
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of 8-chloro-benzo[c]quinolizin
✍ Antonio Guarna; Ernesto G. Occhiato; Dina Scarpi; Chiara Zorn; Giovanna Danza; A 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 175 KB

AbstractÐThe synthesis of a series of dierently substituted 8-chloro-benzo[c]quinolizin-3-ones, as potent and selective human steroid 5a-reductase type 1 inhibitors, has been accomplished by a four-step procedure based on the TiCl 4 -promoted tandem Mannich±Michael cyclization of 2-silyloxy-1,3-buta

Synthesis of 4,17-diazasteroid inhibitor
✍ Jacek W. Morzycki; Zenon z.xl;Lotowski; Agnieszka Z. Wilczewska; J. Darren Stuar 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 566 KB

The synthesis of the 17-aza isomer of finasteride is described. With the side chain amide group of the compound existing in the Z configuration the structure is similar to one of the two favored conformations of finasteride. A series of 4.17-diazasteroids was assayed against the isoenzymes of human