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Synthesis of 5,8,11-dodecatriynoic acid and its use in the synthesis of arachidonic acid and related acids

✍ Scribed by Fryer, R. Ian; Gilman, Norman W.; Holland, Betty C.


Book ID
127371605
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
450 KB
Volume
40
Category
Article
ISSN
0022-3263

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Synthesis of arachidonic acid and relate
✍ D. van der Steen; H. J. J. Pabon; D. A. van Dorp πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 560 KB

## Abstract The usefulness of hexa‐2,5‐diyn‐1‐ol as an intermediate in the synthesis of arachidonic acid, poly‐yn alcohols and docosa‐4,7,10,13,16,19‐hexaynoic acid is demonstrated. Difficulties in the partial reduction of the latter product to the corresponding all cis‐hexaenoic acid are described