Synthesis of 5,6-dihydro-8-methoxy-4H-imidazo[4,5,1-ij]quinolines and some related ring systems
β Scribed by Leslie M. Werbel; Josephine Battaglia; Maria L. Zamora
- Book ID
- 112121760
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1968
- Tongue
- English
- Weight
- 536 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0022-152X
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## Abstract (__R__)β5β(diallylamino)β5,6βdihydroβ4__H__βimidazo[4,5,1β__ij__]quinolinβ2(1__H__)βone (__12b__) was prepared in 9% overall yield from 3βaminoquinoline. Reaction of __12b__ in ethyl acetate with tritium gas in presence of a 5% platinum on carbon catalyst afforded a mixture of (__R__)β5
Synthesis and Diuretic Activity of 4,5-Dihydro-6H-imidazo[4,5,1ij]quinoline-6-one 6-Oxime-O-sulfonic Acid Derivatives. -Among a variety of prepared title compounds, e.g. (I), (II), and (III), derivatives (I) show diuretic activity comparable, cf. (Ia) and (Ib), or superior, cf. (Ic), to that of M17