Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de]phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij]thieno[2,3-c]quinoline 4,4-dioxide
✍ Scribed by Umberto M. Battisti; Marina M. Carrozzo; Giuseppe Cannazza; Daniela Braghiroli; Carlo Parenti; Livio Brasili; Cinzia Citti; Luigino Troisi
- Book ID
- 113930440
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- French
- Weight
- 287 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4039
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**Synthesis of 5,6‐Dimethyl‐4‐oxo‐1,3,4,5‐tetrahydro‐imidazo[4,5‐__c__][1,2,6]thiadiazin 2,2‐dioxide and 7‐Methyl‐4‐oxo‐1__H__‐3,4‐dihydropyrimido[4,5‐__c__][1,2,6]thiadiazin 2,2‐dioxide** The derivatives of the above heterocyclic ring systems were prepared by reaction of the corresponding __o__‐am
## Abstract (__R__)‐5‐(diallylamino)‐5,6‐dihydro‐4__H__‐imidazo[4,5,1‐__ij__]quinolin‐2(1__H__)‐one (__12b__) was prepared in 9% overall yield from 3‐aminoquinoline. Reaction of __12b__ in ethyl acetate with tritium gas in presence of a 5% platinum on carbon catalyst afforded a mixture of (__R__)‐5