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Synthesis of 5-substituted nucleosides via the regioselective lithiation of 2′-deoxyuridine

✍ Scribed by Robert W. Armstrong; Saaket Gupta; Fayelle Whelihan


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
272 KB
Volume
30
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Synthesis of 2′,5′-
✍ Hideyuki Sugimura; Yoshiko Katoh 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Synthesis of 2',5'-Dideoxy-5'-Substituted Pyrimidine Nucleosides via Intramolecular Glycosylation. -5'-Azido and 5'-arylthio-5-deoxypyrimidine nucleosides are synthesized employing intramolecular glycosylation, in which a reaction intermediate is treated in situ with an azide salt or thiol. In some