𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Synthesis of 2′,5′-Dideoxy-5′-Substituted Pyrimidine Nucleosides via Intramolecular Glycosylation.

✍ Scribed by Hideyuki Sugimura; Yoshiko Katoh

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

Synthesis of 2',5'-Dideoxy-5'-Substituted Pyrimidine Nucleosides via Intramolecular Glycosylation.

-5'-Azido and 5'-arylthio-5-deoxypyrimidine nucleosides are synthesized employing intramolecular glycosylation, in which a reaction intermediate is treated in situ with an azide salt or thiol. In some cases the eliminated phenylthiolate acts as the nucleophile affording derivative (Va).

📜 SIMILAR VOLUMES

ChemInform Abstract: Stereocontrolled Sy
ChemInform Abstract: Stereocontrolled Synthesis of β-2′-Deoxypyrimidine Nucleosides via Intramolecular Glycosylations.
✍ X. XIA; J. WANG; M. W. HAGER; N. SISTI; D. C. LIOTTA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

Stereocontrolled Synthesis of β-2'-Deoxypyrimidine Nucleosides via Intramolecular Glycosylations. -In continuation of efforts to develop general methods for the exclusive formation of β-nucleosides, the base-promoted reaction of the pentafuranoside (II) with allyloxypyrimidines (II) is reported. Af

ChemInform Abstract: Stereoselective Syn
ChemInform Abstract: Stereoselective Synthesis of 2′,3′-Dideoxy-nucleosides via Intramolecular Glycosylation of Phenyl 1-Seleno-glycosides. Synthesis of 2′,3′-Dideoxythymidine.
✍ J. LLUIS; M. I. MATHEU; S. CASTILLON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Stereoselective Synthesis of 2',3'-Dideoxy-nucleosides via Intramolecular Glycosylation of Phenyl 1-Seleno-glycosides. Synthesis of 2',3'-Dideoxythymidine. -The intramolecular glycosylation of the coupling products (III) is examined. However, treatment with AgO-Tf and NaOH results only in the isol