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ChemInform Abstract: Facile Synthesis of 5′-Deoxy- and 2′,5′-Dideoxy-6-thiopurine Nucleosides by Nucleoside Phosphorylases.

✍ Scribed by W.-G. CHAE; T. C. K. CHAN; C. CHANG


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of 2′,5′-
✍ Hideyuki Sugimura; Yoshiko Katoh 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB

Synthesis of 2',5'-Dideoxy-5'-Substituted Pyrimidine Nucleosides via Intramolecular Glycosylation. -5'-Azido and 5'-arylthio-5-deoxypyrimidine nucleosides are synthesized employing intramolecular glycosylation, in which a reaction intermediate is treated in situ with an azide salt or thiol. In some