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Synthesis of 5-(Pyridinyl and Pyridiniumyl)-2′-deoxyuridine Nucleosides: Reversible Electron Traps for DNA.

✍ Scribed by Samir T. Gaballah; Thomas L. Netzel


Publisher
John Wiley and Sons
Year
2003
Weight
104 KB
Volume
34
Category
Article
ISSN
0931-7597

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Synthesis of 5-(2-Pyrenyl)-2′-deoxyuridi
✍ Claudia Wanninger-Weiß; Hans-Achim Wagenknecht 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

## Abstract 5‐(2‐Pyrenyl)‐2′‐deoxyuridine (2PydU, **2**) has been prepared as a new thymidine analogue in which the 2‐position of the pyrene chromophore is connected covalently to the 5‐position of uridine through a single C–C bond. The synthesis of **2** starts with the conversion of pyrene (**3**