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Synthesis of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazin-1-ylsulfonyl]-2-n-propoxyphenyl}-7-n-propyl-3,5-dihydro-4H-pyrrolo[3,2-d]-[2-14C]pyrimidin-4-one·2 HCl (14C-SK3530·2 HCl)

✍ Scribed by Hyun-Il Shin; Juyoung Lee; Dae-Kee Kim

Publisher
John Wiley and Sons
Year
2006
Tongue
French
Weight
185 KB
Volume
49
Category
Article
ISSN
0022-2135

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✦ Synopsis

HCl) was synthesized through a straightforward six-step sequence from the readily available [ 14 C-carbonyl]methyl salicylate (2). The overall radiochemical yield of the 1 . 2 HCl from 2 was 10.5%, and its radiochemical purity was 98.8%.

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