Several mono-and bi-cyclic polyhydroxylated alkaloids, isolated from plants', are specific and potent glycosidase inhibitors3, including those involved in the processing of glycoproteins4. Convenient intermediates for the synthesis of these compounds are 5-azido-5-deoxy sugar derivatives. Attempts
Synthesis of 5-deoxy-5-C-(diphenylphosphinyl)-1,2-O-isopropylidene-3-O-methyl-β-l-idofuranose
✍ Scribed by Manabu Yamada; Mitsuji Yamashita; Saburo Inokawa
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 155 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0008-6215
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## Carbohydrates U 0500 Hydroxy Group Interactions in Stannylated Carbohydrates
For the synthesis of 4-methylcoumarin-7-yl cY-L-idopyranosiduronic acid, a convenient, sensitive substrate' for a-L-iduronidase (EC 3.2.1.76), we required quantities of suitable L-idopyranose derivatives. During the course of this work, a novel synthesis of L-idose (1) was reported\*, and has now be
The structures of the title compounds (2b and 3) have been investigated in the solid state by X-ray methods. The crystals of 2b are monoclinic, space group P2,, and of 3 orthorhombit, space grtup P2,2,2,. The cell dimensions are: for 2b, a = 9.910(2), b = 11;745W, c = 11.810(3) A, /3 = 97.32(l)"; a