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Synthesis of 5′-deoxy-5′-[18F]fluoro-adenosine by Radiofluorination of 5′-deoxy-5′-haloadenosine Derivatives

✍ Scribed by Sz. Lehel; G. Horváth; I. Boros; P. Mikecz; T. Márián; L. Trón


Book ID
110241256
Publisher
Springer
Year
2000
Tongue
English
Weight
140 KB
Volume
245
Category
Article
ISSN
1588-2780

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✍ Ba V. Nguyen; Chentao York; Tomas Hudlicky 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 587 KB

Two deoxyfluoroinositols were synthesized from bromocyclohexadiene cis-diol obtained by microbial oxidation of bromobenzene with P. putidu (39D). The selective introduction of fluorine was accomplished by opening of the epoxide with teuabutylphosphoniumtluoride dihydrofluoride (TBPF-DF). The synthe