Fluorinase-Coupled Base Swaps: Synthesis of [18F]-5′-Deoxy-5′-fluorouridines
✍ Scribed by Margit Winkler; Juozas Domarkas; Lutz F. Schweiger; David O'Hagan
- Book ID
- 101542137
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 336 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Biology Department, U n i v e r s i t y of C a l i f o r n i a , San Diego, L a J o l l a , CA \*\* A r a p i d s y n t h e s i s of 5'-deoxy-5-[ 1 8 F ] f l u o r o u r i d i n e (?\_a) from e i t h e r a c i a l acetic a c i d at room temperature followed by h y d r o l y s i s with sodium methox
## Abstract Synthesis of 2′‐deoxy‐2′‐[^18^F]fluoro‐5‐methyl‐1‐__β__‐D‐arabinofuranosyluracil ([^18^F]‐FMAU) is reported. 2‐Deoxy‐2‐[^18^F]fluoro‐1,3,5‐tri‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** was prepared by the reaction of the respective triflate **1** with tetrabutylammonium[^18^F]fluoride. Th