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Synthesis of 4-thiamethionine and its effect on energy metabolism and amino acid incorporation into protein of Ehrlich ascites tumour cells

โœ Scribed by M. Rabinovitz; J.M. Johnson


Book ID
115767557
Publisher
Elsevier Science
Year
1961
Tongue
English
Weight
556 KB
Volume
7
Category
Article
ISSN
0006-2952

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o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites