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Antitumor agents XXIX: Effects of eupahyssopin on nucleic acid, protein, anaerobic, and aerobic metabolism of ehrlich ascites tumor cells

โœ Scribed by Iris H. Hall; Kuo-Hsiung Lee; Salwa A. Eigebaly

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
557 KB
Volume
67
Category
Article
ISSN
0022-3549

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โœ Iris H. Hall; Y. F. Liou; K. H. Lee ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 551 KB

o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites