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Effects of 3-chloromethylthiochromone-1,1-dioxide on nucleic acid, protein, and aerobic and anaerobic metabolism of ehrlich ascites tumor cells

โœ Scribed by Mark H. Holshouser; Larry J. Loeffler; Iris H. Hall


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
695 KB
Volume
71
Category
Article
ISSN
0022-3549

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Antitumor agents LII: The effects of mol
โœ Iris H. Hall; Y. F. Liou; K. H. Lee ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 551 KB

o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites