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Synthesis of 4-substituted glutarimides by free radical addition of iodoacetamide to α,β-unsaturated esters

✍ Scribed by Guerino Sacripante; Charles Tan; George Just


Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
212 KB
Volume
26
Category
Article
ISSN
0040-4039

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✦ Synopsis


Free radica2 addition of either methyl bromoacetate or iodoacetamide to an cl, B-unsaturated ester gave the 4-substituted ghtarate or glutarimide respectively, whereas the radical cycZisation of N-bromoacetyl crotonamide gave the &substituted succinimide.


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