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Conjugate addition of amides to α,β-unsaturated esters by CsF-Si(OEt)4 system

✍ Scribed by Kyo Han Ahn; Seok Jong Lee


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
273 KB
Volume
35
Category
Article
ISSN
0040-4039

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✦ Synopsis


The conjugate addidon of amides to cx&unsawared esters proceeds &kiendy with an equimolar amount of Si(OEr)d and a catalytic wnount of CsF w crfford the corresponding N-substituted amides.


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Synthesis of 4-substituted glutarimides
✍ Guerino Sacripante; Charles Tan; George Just 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 212 KB

Free radica2 addition of either methyl bromoacetate or iodoacetamide to an cl, B-unsaturated ester gave the 4-substituted ghtarate or glutarimide respectively, whereas the radical cycZisation of N-bromoacetyl crotonamide gave the &substituted succinimide.