Nickel-Catalyzed 1,4-Addition of Trialkylboranes to α,β-Unsaturated Esters: Dramatic Enhancement by Addition of Methanol.
✍ Scribed by Koji Hirano; Hideki Yorimitsu; Koichiro Oshima
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 35 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract The asymmetric rhodium‐catalyzed 1,4‐addition of sodium tetraalkylborates to β,β‐disubstituted α,β‐unsaturated esters creates quaternary carbon stereocenters with high enantioselectivity.
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