Synthesis of 4-Methyl-1,2,3-thiadiazole Derivatives via Ugi Reaction and Their Biological Activities †
✍ Scribed by Zuo, Xiang; Mi, Na; Fan, Zhijin; Zheng, Qingxiang; Zhang, Haike; Wang, Huan; Yang, Zhikun
- Book ID
- 120090825
- Publisher
- American Chemical Society
- Year
- 2010
- Tongue
- English
- Weight
- 777 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0021-8561
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## Abstract The aminothiadiazole (II) on treatment with aromatic aldehydes yielded Schiff bases, which cyclized to thiazolidinone derivatives by reaction with thioglycolic acid. Reaction of II with phenyl isocyanate and phenyl isothiocyanate afforded the carbamide and carbothiamide derivatives, res