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Synthesis of 4-alkyl-substituted 1,2,3,4-tetrahydropyrimidin-2-ones by the Biginelli reaction

โœ Scribed by A. D. Shutalev; N. V. Sivova


Publisher
Springer US
Year
1998
Tongue
English
Weight
285 KB
Volume
34
Category
Article
ISSN
0009-3122

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## Abstract 1โ€(Aralkyl/aryl)โ€3โ€(alkyyaralkyl)โ€5โ€aroylโ€1,2,3,4โ€tetrahydropyrimidines (**2aโ€c**) have been synthesized by dethiomethylation of 5โ€aroylโ€6โ€methylthioโ€1,2,3,4โ€tetrahydropyrimidines (**1aโ€c**). An alternative oneโ€pot synthetic strategy has been developed for the title compounds **2aโ€t** b