Synthesis of 3β-hydroxy-5α-cholest-8-en-7-one and 3β-hydroxy-5α-cholest-8-en-11-one: Evaluation as potential hypocholesterolemic agents
✍ Scribed by Edward J. Parish; Venkata B.B. Nanduri; Jean M. Seikel; Herbert H. Kohl; Kenneth E. Nusbaum
- Book ID
- 116065091
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 649 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0039-128X
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
Reaction of 36-benzyloxy-5-hydroxy-5a-cholestan-6-one (1) with potassium t-butoxide in t-butyl alcohol gives 5-hydroxy-56-cholest-3-en-6-one (2), which on direct irradiation (300 nm) ?-n hexanes gives the B-seco steroid 9 and the indenacetaldehyde derivative 10.