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Synthesis of 3a,6,6,9a-tetramethyl-trans-perhydronaphtho [2,1-b]furan and 4a,7,7,10a-tetramethyl-trans-perhydronaphtho [2,1-b]pyran

✍ Scribed by P. F. Vlad; N. D. Ungur; V. B. Perutskii

Publisher
Springer US
Year
1990
Tongue
English
Weight
520 KB
Volume
26
Category
Article
ISSN
0009-3122

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πŸ“œ SIMILAR VOLUMES

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Synthesis of bridged analogs of epibatid
Synthesis of bridged analogs of epibatidine. 3-Chloro-5,7,8,9,9a,10-hexahydro-7,10-methanopyrrolo[1,2-b]-2,6-naphthyridine and 2-chloro-5,5a,6,7,8,10-hexahydro-5,8-methanopyrrolo[2,1-b]-1,7-naphthyridine
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The synthesis of conformationally locked analogs of epibatidine are described in which the key step is an intramolecular reductive palladium-catalyzed Heck-type coupling.