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4,4,7,7-Tetramethyl-2-tosyl-2,3,3a,4,6,7,8,9-octahydro-1H-pyrrolo[3,4-c]pyrano[6,5-b]cyclohexan-9-one

โœ Scribed by Chinnakali, K. ;Sudha, D. ;Jayagopi, M. ;Raghunathan, R. ;Fun, Hoong-Kun

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
835 KB
Volume
63
Category
Article
ISSN
1600-5368

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โœฆ Synopsis

The title compound, C~22~H~29~NO~4~S, crystallizes with three independent molecules, A, B and C, in the asymmetric unit. Each of the three independent molecules adopts a folded conformation, with the phenylsulfonyl group lying over the pyranocyclohexanone ring system, and with the pyrrolidine and dihydropyran rings cis-fused. In all three molecules, the pyrrolidine ring has a twist conformation and the dihydropyran ring is in a half-chair conformation. The cyclohexenone rings adopt envelope conformations, with the flap atom puckered towards the phenylsulfonyl group in molecule A, and away from that group in molecules B and C, resulting in a different overall conformation for molecule A compared to B and C. In all molecules, the tosyl group is equatorially attached to the pyrrolidine ring. In the crystal structure, the molecules are linked into a three-dimensional framework by Cโ€”H...O hydrogen bonds.

๐Ÿ“œ SIMILAR VOLUMES

1-Ethyl-4,4,6,8-tetramethyl-2-tosyl-2,3,
1-Ethyl-4,4,6,8-tetramethyl-2-tosyl-2,3,3a,4,6,7,8,9-octahydro-1H-pyrrolo[3,4-c]pyrano[6,5-d]pyrimidine-7,9-dione
โœ Chinnakali, K. ;Sudha, D. ;Jayagopi, M. ;Raghunathan, R. ;Fun, Hoong-Kun ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› International Union of Crystallography ๐ŸŒ English โš– 913 KB

The asymmetric unit of the title compound, C~22~H~29~N~3~O~5~S, contains two independent molecules, __A__ and __B__, which differ slightly in the orientation of the ethyl and tosyl groups with respect to the attached pyrrolidine ring, as evidenced by the relevant torsion angles. In both molecules, t

4,4,6,8-Tetramethyl-2-tosylpyrrolo[3,4-c
4,4,6,8-Tetramethyl-2-tosylpyrrolo[3,4-c]pyrano[6,5-b]pyrimidine-7,9-dione
โœ Chinnakali, K. ;Jayagopi, M. ;Sudha, D. ;Raghunathan, R. ;Fun, Hoong-Kun ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› International Union of Crystallography ๐ŸŒ English โš– 1013 KB

In the title compound, C~20~H~25~N~3~O~5~S, the pyrrolidine ring is __trans__-fused to the dihydropyran ring. The pyrrolidine ring adopts a twist conformation and the dihydropyran ring is in an envelope conformation. The tosyl group is attached to the pyrrolidine ring in a biaxial position and its b

9-(4-Bromophenyl)-3,3,6,6-tetramethyl-3,
9-(4-Bromophenyl)-3,3,6,6-tetramethyl-3,4,6,7-tetrahydro-2H-xanthene-1,8(5H,9H)-dione
โœ Bigdeli, M. Ali ;Mahdavinia, Gholam Hossein ;Amani, Vahid ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› International Union of Crystallography ๐ŸŒ English โš– 646 KB

The title compound, C 23 H 25 BrO 3 , was synthesized by the reaction of p-bromobenzaldehyde with dimedone and HClO 4 / SiO 2 in EtOH. In the molecule, the dihydropyran ring adopts a boat conformation and the two cyclohexene rings are in a trans conformation.

6-(4-Chlorophenyl)-9,9-dimethyl-3,7-diox
6-(4-Chlorophenyl)-9,9-dimethyl-3,7-dioxo-2,3,4,6,7,8,9,10-octahydro-1H-pyrimido[1,2-a]quinoline-5-carbonitrile
โœ Chen, Dong-Qin ;Li, Chun-Mei ;Tu, Shu-Jiang ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› International Union of Crystallography ๐ŸŒ English โš– 873 KB

The title compound, C 21 H 20 ClN 3 O 2 , was synthesized by the reaction of 4-chlorobenzaldehyde and 3-(5,5-dimethyl-3-oxocyclohex-1-enylamino)propanoic acid with malononitrile in ethylene glycol under microwave irradiation. The dihydropyridine ring has a boat conformation. The pyrimidine ring adop