Three syntheses o f r a d i o l a b e l l e d 2-[2-(2-N.N-Dlmethylarnlnomethyl-5 -f uranyl-methyl thlo)ethylamlno]-5-( 6-hydroxy-l-plcolyl ) -4pyrlmldone t r i h y d r o c h l o r l d e (donetldlne t r i h y d r o c h l o r i d e ) are described. One descrlbes the preparatlon o f the f r e e base, a
Synthesis of 35S- and 14C-labeled famotidine, a new potent histamine H2 receptor antagonist
β Scribed by Kazuharu Tamazawa; Hideki Arima
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- French
- Weight
- 272 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0022-2135
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## Abstract 1βBenzylβ4βhydroxy[2β^14^C]piperidine, a useful intermediate in labeled compound synthesis, was prepared from [^14^C]formaldehyde in high yield. The distribution pattern of ^14^C in the product is consistent with a mechanism involving reversible iminium ion formation and rapid equilibra
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v