## Abstract Pyrazolo‐[3,4‐__d__]pyrimidine‐4,6‐diones **5** and pyrazolo[4,3‐__d__]pyrimidine‐5,7‐diones **7** were synthesized by Curtius rearrangement of pyrazolic mono‐esters **2** and **3** followed by hetero‐cyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.
Synthesis of 3-(β-D-ribofuranosyl)-5,7-dihydroxy-1H-pyrazolo/4,3-d/pyrimidine
✍ Scribed by M. Bobek; J. Farkaš; F. Šorm
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- French
- Weight
- 211 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0040-4039
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Synthesis of 4-Substituted 1-((2,3-Dihydroxy-1-propoxy)methyl)-1Hpyrazolo (3,4-d)pyrimidines. -The regioselective synthesis of a series of acyclonucleosides of pyrazolopyrimidines (cf. (IV), (V), (VII), (IX)) is described. The obtained compounds are evaluated for their cytotoxicity and anti-HIV act
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