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A convenient synthesis of pyrazolo[3,4-d]pyrimidine-4,6-dione and pyrazolo[4,3-d]pyrimidine-5,7-dione derivatives

✍ Scribed by M. El Haddad; M. Soukri; S. Lazar; A. Bennamara; G. Guillaumet; M. Akssira

Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
470 KB
Volume
37
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Pyrazolo‐[3,4‐d]pyrimidine‐4,6‐diones 5 and pyrazolo[4,3‐d]pyrimidine‐5,7‐diones 7 were synthesized by Curtius rearrangement of pyrazolic mono‐esters 2 and 3 followed by hetero‐cyclization via the ureas derivatives 4 and 6 under alkaline conditions.

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