Synthesis of 3-substituted 2-aryloxazolidine-4,5-diones
β Scribed by Yu. S. Andreichikov; Yu. V. Ionov; I. A. Balykova
- Book ID
- 112349159
- Publisher
- Springer US
- Year
- 1982
- Tongue
- English
- Weight
- 53 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0009-3122
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π SIMILAR VOLUMES
Novel 2,3-substituted-2,4-dihydro-pyrazolo[4,3-d] pyrimidine-5,7-diones were successfully synthesized with moderate to good yields using a new synthetic approach. The structures of the regio-isomers in this series were determined by single crystal X-ray analysis and NMR spectra.
Monoor dibromo derivatives 2 and 3 were prepared by an efficient two-step route from 10-methyl-azepino [3,4-b]indole-1,5dione 1. Elimination reaction on 2 gave access to 4-bromo-10-methyl-2H,10H-azepino[3,4-b]indole-1,5-diones 4. Finally, 4-substituted 10methyl-2H,10H-azepino [3,4-b]indole-1,5-dione