with good yield in t w o steps f r o m Na14CN, starting from 14-methyl 1-phenyl-tetradecanol methanesulfonate with a specific radioactivity : 108.25 pCi/mg, 1.92 mCilmmo1. and in a radiochemical yield of 50% of the theoretical amount. p-Methyl-15-phenyl-pentadecanoic acid labelled with carbon-14 wa
Synthesis of 3-methyl-15-(p-iodophenyl)-pentadecanoic acid labelled with carbon-14
✍ Scribed by T. Humbert; C. Luu-Duc; D. Le Bars; A. Marsura
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 145 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Methyl-(p-iodophenyll-pentadecanoic acid 5 labelled with carbon-14 in the carboxyl group was obtained in 38% radiochemical yield in five steps from Na 1 4 CN a t a specific radioactivity of 0.084 mCi/mg, 38.6 mCi/mmol.
📜 SIMILAR VOLUMES
The preparation of 14f41abeled (\*)-2-methyl-3,3-diphenyl-3propanolamine (2) from [ Cl-carbonyl-benzophenone is described.
## Abstract The synthesis of isotopomers of phenylpyruvic acid, PPA, selectively labeled with hydrogen isotopes in the 3‐position of the side‐chain is reported. Three deuterium or tritium labeled isotopomers of L‐phenylalanine, L‐Phe, i.e. [(3__S__)‐^2^H]‐L‐, [(3__S__)‐^3^H]‐L‐, and doubly labeled
## Abstract The title product was labelled with ^14^C at the ketone group, from 3‐methoxybromobenzene in six steps. Complete synthetic techniques of the labelled drug are presented.
## Abstract O,O‐Dimethyl O‐(3‐methyl‐4‐nitrophenyl) phosphorothioate (I) (Sumithion®), an organophosphorus insecticide, was labelled with carbon‐14 individually at the aryl methyl and the phenyl ring. The synthetic procedures are shown in Fig. 1 and 2. Coupling reaction of 3‐methoxyphenylmagnesium