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Synthesis of (2S, 5S)-2,5-dimethoxyadipic acid

✍ Scribed by A. I. Gurevich; M. N. Kolosov; V. V. Kudryashova


Book ID
112438044
Publisher
Springer
Year
1974
Tongue
English
Weight
134 KB
Volume
23
Category
Article
ISSN
1573-9171

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Synthesis of (2S, 5R) - [5-2H] Proline
✍ Paola Gramatica; Paolo Manitto; Ada Manzocchi; Enzo Santaniello πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 French βš– 318 KB

## Abstract The title compound was obtained by preferential crystallisation of (2RS,5R)‐[5‐^2^H]proline. The labelled racemic amino acid was synthesized in five steps from (5R)‐[5‐^2^H]‐2‐pyrrolidone, which was prepared by cyclisation of (4R)‐[4‐^2^H] GABA. The stereospecific label was introduced i