## Abstract Lipase‐catalyzed transesterifications and biological reductions were used to obtain the (__S__)‐enantiomers of 3‐chloro‐1‐(1,3‐dithian‐2‐yl)‐2‐propanol and 1‐(1,3‐dithian‐2‐yl)‐3‐fluoro‐2‐propanol and their (__R__)‐acetates. (__S__)‐3‐Chloro‐1‐(1,3‐dithian‐2‐yl)‐2‐propanol and (__R__)‐3
Synthesis of (2R,3R)- and (2S,3S)-[2,3-2H2]oxirane and application of it to the synthesis of chirally labeled homoserine
✍ Scribed by Schwab, John M.; Ray, Tapan; Ho, Chorng Kei
- Book ID
- 111892814
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 884 KB
- Volume
- 111
- Category
- Article
- ISSN
- 0002-7863
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## Abstract α‐Deuterated tryptophan was prepared either by exchange of the α‐hydrogen of tryptophan or by hydrolysis and decarboxylation of ethyl 2‐formamido‐2‐carbethoxy‐3‐indole propionate, followed by treatment with CH~3~COO^2^H. α,β‐Dideuterated tryptophan was in turn synthetized from ethyl‐α‐a