## Abstract α‐Deuterated tryptophan was prepared either by exchange of the α‐hydrogen of tryptophan or by hydrolysis and decarboxylation of ethyl 2‐formamido‐2‐carbethoxy‐3‐indole propionate, followed by treatment with CH~3~COO^2^H. α,β‐Dideuterated tryptophan was in turn synthetized from ethyl‐α‐a
Synthesis of (2R)- and (2S)-[3-2H]-valine
✍ Scribed by Christopher J. Easton; Nicola G. Findlay
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- French
- Weight
- 186 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-2135
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## Abstract A practical synthesis of (2R)‐ and (2S)‐[2‐^3^H]‐propionic acid is described. The key steps in the synthesis are the reduction of [__formyl__‐^3^H]‐3‐methoxy‐4‐mesyloxybenzaldehyde with R‐ or S‐Alpine Borane to (7S)‐ and (7R)‐[7‐^3^H]‐3‐methoxy‐4‐mesyloxybenzyl alcohol and the use of th
## Abstract (R)‐(−) Benzoin oxime **2** was catalytically tritiated to afford [2‐^3^H] (1R,2S)‐(−)‐2‐amino‐1,2‐diphenylethanol **1** in 92% ee. Copyright © 2001 John Wiley & Sons, Ltd.