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Synthesis of 2,6-Dideoxysugars via Ring-Closing Olefinic Metathesis

โœ Scribed by Andreana, Peter R.; McLellan, Jason S.; Chen, Yongchen; Wang, Peng George


Book ID
120255768
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
117 KB
Volume
4
Category
Article
ISSN
1523-7060

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The 1-benzazepin-2-one ring system is an important structural feature of marketed drugs, clinical candidates, and other bioactive molecules. We have developed a new benzazepinone synthesis that employs ring-closing olefin metathesis as a key step. This route provides efficient access to substituted