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Synthesis of [25R]- and [25S]-25,26-dihydroxyvitamin D3

✍ Scribed by Naoyuki Koizumi; Masuo Morisaki; Nobuo Ikekawa

Publisher: Elsevier Science
Year: 1978
Tongue: French
Weight: 226 KB
Volume: 19
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)94893-2

No coin nor oath required. For personal study only.

✦ Synopsis

In addition to the la-hydroxy group essential for eliciting biological activity, vitamin D3 metabolites bear the hydroxyl function in side chain at C-24, C-25 and/or C-26.2 Among those, the absolute configuration at C-24 in the 24-hydroxylated metabolites, 24,25_dihydroxyvitamin D33 and 1,24,25_trihydroxy-

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