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Synthesis of (24S)- and (24R)-1α-hydroxy-[24-3H]-cholecalciferol

✍ Scribed by Bannai Kiyoshi; Ishizuka Seiichi; Naruchi Tatsuyuki; Hashimoto Yoshinobu


Book ID
116001723
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
749 KB
Volume
10
Category
Article
ISSN
0022-4731

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Couphng of the CD fragment, ketone 6 (obtamed by pamal synthesis from vitanun D2). either directly (Homer-Wmlg route) or via the denved enol mflate (dlenyne route) with the appropnate A-ring fragment, phosphme oxide amon 7 or enyne 10, 1s the key step m the syntheses of 24-oxavmunm D3 (ld) and la-hy