Synthesis of 2,3-Disubstituted 4-Oxoquinolines and 3-Substituted Fused 4-Oxoquinolines
✍ Scribed by Z. Alkhathlan, Hamad; A. Al-Farhan, Khalid
- Book ID
- 111676125
- Publisher
- Japan Institute of Heterocyclic Chemistry
- Year
- 1998
- Tongue
- English
- Weight
- 333 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0385-5414
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📜 SIMILAR VOLUMES
A series of new ribonucleosides 1a-d having 4-oxoquinoline-3-carboxylic acid substituted with a chloro or bromo atom in the aromatic ring, as the nitrogen base, was synthesized and examined for anti-HIV activity. Compounds 1a and 1c showed a modest inhibition activity on HIV-1 reverse transcriptase,
## Abstract 4‐Azido‐2‐oxoquinoline‐3‐carboxylates and 4‐azidocoumarin‐3‐carboxylates 6, which were obtained from the corresponding 4‐hydroxy derivatives 1 __via__ 4‐tosylates 2 or 4‐chloro compounds 4, cyclized upon thermolysis to 3‐alkoxyisoxazolo[4,3‐__c__]quinolin‐4(5__H__)‐ones or the correspon