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Direct monobromination of substituted 4-oxoquinoline-3-carboxylic acid derivatives

✍ Scribed by Irena Moẑek; Boris Ŝket


Book ID
112131033
Publisher
Journal of Heterocyclic Chemistry
Year
1994
Tongue
English
Weight
176 KB
Volume
31
Category
Article
ISSN
0022-152X

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Synthesis of novel nucleosides of 4-oxoq
✍ Anderson D. da Matta; Carla Verônica B. dos Santos; Helena de S. Pereira; Izabel 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB 👁 2 views

A series of new ribonucleosides 1a-d having 4-oxoquinoline-3-carboxylic acid substituted with a chloro or bromo atom in the aromatic ring, as the nitrogen base, was synthesized and examined for anti-HIV activity. Compounds 1a and 1c showed a modest inhibition activity on HIV-1 reverse transcriptase,