Synthesis of novel nucleosides of 4-oxoq
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Anderson D. da Matta; Carla Verônica B. dos Santos; Helena de S. Pereira; Izabel
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Article
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1999
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John Wiley and Sons
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English
⚖ 150 KB
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A series of new ribonucleosides 1a-d having 4-oxoquinoline-3-carboxylic acid substituted with a chloro or bromo atom in the aromatic ring, as the nitrogen base, was synthesized and examined for anti-HIV activity. Compounds 1a and 1c showed a modest inhibition activity on HIV-1 reverse transcriptase,