Synthesis of 2,2,6-trisubstituted 1,3-dioxen-4-ones
β Scribed by Yu. S. Andreichikov; L. G. Gein; V. L. Gein
- Book ID
- 112327983
- Publisher
- Springer US
- Year
- 1979
- Tongue
- English
- Weight
- 54 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0009-3122
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## Abstract For Abstract see ChemInform Abstract in Full Text.
A novel method for the synthesis of 1,2,4-trisubstituted-or 1,2,3,4-tetrasubstituted-1,2,5,6-tetrahydropyridine is presented. The process was carried out by the bromomethoxylation of 4-substituted-1,2,5,6-tetrahydropyridines 1 with N-bromosuccinimide (NBS) in methanol, dehydrobromination with 1,8-di
The solid phase synthesis of 2,4,5-trisubstituted thiomorpholin-3-ones is described. Starting from a resin-bound protected cysteine, and employing reductive alkylation and amide formation, thiomoq~holin-3one derivatives have been synthesized through intramolecular thioether formation in good yield a