Synthesis of 22,23-Epoxyecdysteroids from Stigmasterol
✍ Scribed by N. V. Kovganko; V. L. Survilo
- Book ID
- 110311920
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 85 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0009-3130
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## Abstract An efficient and short synthesis of 28‐homobrassinolide (6) has been achieved in 12 steps with 15.6% overall yield from stigmasterol (8). Salient features of this synthesis are: (a) use of tetradecyltrimethylammonium permanganate for chemoselective __cis__‐dihydroxylation of the 2,22__E
## Abstract Antheridiol‐(22,23‐^3^H) has been prepared by reduction of 3‐acetoxy‐23,23‐dihydroxy‐22‐oxo‐5, 24(28)‐ergostadiene‐28‐carboxylic acid gamma ‐ lactone with tritiated sodium borohydride followed by hydrolysis, photo‐oxygenation and cupric chloride catalysed rearrangement.