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A convenient synthesis of progesterone from stigmasterol

✍ Scribed by Sundararaman, Padmanabhan; Djerassi, Carl


Book ID
126785561
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
164 KB
Volume
42
Category
Article
ISSN
0022-3263

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## Abstract An efficient and short synthesis of 28‐homobrassinolide (6) has been achieved in 12 steps with 15.6% overall yield from stigmasterol (8). Salient features of this synthesis are: (a) use of tetradecyltrimethylammonium permanganate for chemoselective __cis__‐dihydroxylation of the 2,22__E