Synthesis of 2-substituted naphth[1,8-de]-1,3-oxazines
✍ Scribed by S. E. Tolchinskii; M. V. Kormer; I. A. Maretina
- Publisher
- Springer US
- Year
- 1991
- Tongue
- English
- Weight
- 180 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0009-3122
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📜 SIMILAR VOLUMES
## Abstract magnified image Alicyclic __N__‐substituted 1,3‐amino alcohols **13‐18** were prepared in a facile way in a one‐pot procedure from 1,3‐oxazines **5‐8** in the presence of a ketone **9‐12**. The complex reaction involves palladium‐catalyzed reduction, debenzylation and/or transimination
## Abstract Derivatives of the unknown 2‐amino‐6__H__‐1,3‐oxazin‐6‐one **2** have been synthesized for the first time in two steps and in excellent yields, starting from __N__‐cyanocarbonimidates **3a**–**c** and cyanoacetates. The structures of **2a**–**c** are assigned by NMR‐spectroscopic method
A novel and facile synthesis of 6-substituted chiral N-aryl-l,3-oxazin-2-one derivatives has been achieved starting from readily available (A)-aspartic acid.
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