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Synthesis of 2-Piperidinecarboxylic Acid and Its Derivatives.

✍ Scribed by A. A. Bazurin; T. A. Obukhova; S. V. Krasnikov; A. F. Betnev; O. N. Ovsyanikov

Publisher
John Wiley and Sons
Year
2005
Weight
21 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract The enantioselective synthesis of the non‐proteinogenic amino acids β‐proline and nipecotic acids from their readily available nitriles is achieved in high enantiomeric excess by commercially available nitrilases. The presented procedure comprises not more than 4 steps, thus considerabl